Ubiquitin Vinyl Sulfone (Ub-VS)
Ubiquitin Vinyl Sulfone (Ub-VS) is a potent and irreversible inhibitor of UCH, USP and OTU families of deubiquitinating enzymes (DUBs). It forms a covalent linkage with the active site Cys residue of a DUB. Ub-VS can be used to profile DUB and modify DUBs for structural determination.
Product Name:
Ubiquitin Vinyl Sulfone (Ub-VS)
>Also Known As:
Ub-VS
>Catalog No.:
M1030
>Size:
50 µg
>Molecular Weight:
8624 Da by MS
>Species:
Human
>Source:
Synthetic
>Stock:
Product in lyophilized powder form.
>Concentration:
N/A
>Quality Assurance:
≥95% by RP-HPLC and SDS-PAGE
>Storage:
Powder at −20°C; solution at −80°C. Avoid multiple freeze/thaw cycles.
>PDF Data Sheet:
PDF Datasheet， MSDS
>NCBI RefSeq:
N/A
>Image(s):
See images in PDF Datasheet
>Shipping Method:
Room temperature shipping
>References:
1. Galardy et al., (2005) Methods in Enzymology 399, 120.
2. de Jong et al., (2012) ChemBioChem 13, 2251. FG-4592 18470320
