GST-UCHL1
Deubiquitinating enzymes (DUBs) are proteases that posses the ability to cleave ubiquitin chains or the isopeptide bond that conjugates ubiquitin with a substrate. Human cells have approximately 100 DUBs that play important roles in regulating various cellular events. UCHL1 is one of the four members of the ubiquitin C-terminal hydrolase (UCH) family. It is thought to be mainly involved in cleaving proubiquitin proteins into monomeric ubiquitin.
Product Name:
GST-UCHL1
>Also Known As:
PARK5; PGP95; PGP9.5; Uch-L1; PGP 9.5
>Catalog No.:
H1110
>Size:
25 µg
>Molecular Weight:
24.8 kDa
>Species:
Human
>Source:
Bacterial recombinant
>Stock:
20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
>Concentration:
See tube label
>Quality Assurance:
~95% by SDS-PAGE, see datasheet for gel image
>Storage:
Store at -80°C; avoid multiple freeze-thaw cycles
>PDF Data Sheet:
PDF Datasheet， MSDS
>NCBI RefSeq:
NM_004181
>Image(s):
N/A
>Shipping Method:
Dry ice shipping
>References:
1. Pickart CM, et al. (1985) J Biol Chem 260(13), 7903 – 7910.
2. Wilkinson KD (1997) FASEB J 11(14), 1245 – 1256.
3. Larsen CN, et al. (1998) Biochemistry 37(10), 3358 – 3368.
4. Reyes-Turcu FE, et al. (2009) Annu Rev Biochem 78, 363 – 397. PT-2385 18468597
