6xHis-Uch37
Uch37 is one of the deubiquitinating enzymes of the human 26S proteasome, belongs to the Ub C-terminal hydrolases. Uch37 was found to bind both Adrm1 and S5a subunits of the 26S proteasome. Uch37 likely contributes to the Ub chain trimming activity of the 26S proteasome that shortens a polyUb chain from the distal end of the chain.
Product Name:
6xHis-Uch37
>Also Known As:
UCHL5;UCH37; CGI-70; INO80R; UCH-L5
>Catalog No.:
A3500
>Size:
25 µg
>Molecular Weight:
37.6 kDa
>Species:
Human
>Source:
Bacterial recombinant
>Stock:
20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
>Concentration:
See tube label
>Quality Assurance:
~95% by SDS-PAGE, see datasheet for gel image
>Storage:
Store at -80°C; avoid multiple freeze-thaw cycles
>PDF Data Sheet:
PDF Datasheet， MSDS
>NCBI RefSeq:
NM_015984
>Image(s):
No
>Shipping Method:
Dry ice shipping
>References:
1. Verma R, et al. (2000) Mol Biol Cell 11(10), 3425 – 3439.
2. Koulich E, et al. (2007) Mol Biol Cell, 19(3) 1072 – 1082.
3. Husnjak K, et al. (2008) Nature 453, 481 – 488.
4. Lee BH, et al. (2010) Nature 467, 179 – 184. (+)-JQ-1 18467962
