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Ramzan et al. Reproductive Biology and Endocrinology 2012, 10:18 http://www.rbej.com/content/10/1/RESEARCHOpen AccessImmature rat seminal vesicles show histomorphological and ultrastructural alterations following treatment with kisspeptin-Faiqah Ramzan1,2*, Irfan Zia Qureshi2, Muhammad Ramzan3, Muhammad Haris Ramzan4 and Faiza RamzanAbstractBackground: Degenerative effects of critical regulators of reproduction, the kisspeptin peptides, on cellular aspects of sexually immature male gonads are known but similar information on accessory sex glands remain elusive. Methods: Prepubertal laboratory rats were injected kisspeptin-10 at three different dosage Chloroquine (diphosphate) site concentrations (10 pg, 1 ng and 1 microgram) for a period of continuous 12 days at the rate of two doses per day. Control rats were maintained in parallel. The day following the end of the experimental period, seminal vesicles were removed and processed for light and electron micr.
