Name:
FGF-8b Protein
Synonyms:
Fibroblast growth factor 8b,FGF8
Species Name:
Human
Label Name:
No Tag
Marker Name:
Unconjugated
Accession:
P55075
Gene Id:
Gln23-Arg215\rMQVTVQSSPNFTQHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR
Molecular Weight:
25kDa (Reducing)
Purity:
＞95% by SDS-PAGE
Physical Appearance Name:
Lyophilized Powder
Endotoxin Name:
<1EU/μg
Reconstitution:
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability Storage:
· 12 months from date of receipt, -20 to -70 °C as supplied. · 6 months, -20 to -70 °C under sterile conditions after reconstitution.· 1 week, 2 to 8 °C under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Buffer System:
Quality Statement:
Fibroblast growth factor 8b (FGF-8b), a secreted heparin-binding protein, is a member of the fibroblast growth factor (FGF) family and is an isoform of FGF-8. Alternative splicing of FGF-8 gene gives rise to potentially four (a, b, e, f) different protein isoforms in human, and FGF-8b exhibits the highest transforming activity in NIH3T3 cells. FGF-8b signals through FGF receptors (FGFRs) to activate PI3K and MAPK pathways. FGF-8b is broadly associated with mitogenic and cell survival activities, and regulates gastrulation, epithelial-mesenchymal transition, and later on mesenchymal to epithelial differentiation during embryonic development. FGF-8b has also been found in peripheral blood leukocytes and healthy bone marrow samples.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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