Name:
IL-7 Protein
Synonyms:
Interleukin-7
Species Name:
Human
Label Name:
His Tag
Marker Name:
Unconjugated
Accession:
P13232
Gene Id:
Asp26-His177 with C-terminal 6*His TagDCDIEGKDGKQYESVLMVSIDQLLDSMKEIGSNCLNNEFNFFKRHICDANKEGMFLFRAARKLRQFLKMNSTGDFDLHLLKVSEGTTILLNCTGQVKGRKPAALGEAQPTKSLEENKSLKEQKKLNDLCFLKRLLQEIKTCWNKILMGTKEHHHHHHH
Molecular Weight:
18-30 kDa (Reducing)
Purity:
＞95% by SDS-PAGE
Physical Appearance Name:
Lyophilized Powder
Endotoxin Name:
<1EU/mg
Reconstitution:
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability Storage:
· 12months from date of receipt, -20 to -70 °C as supplied. · 6months, -20 to -70 °C under sterile conditions after reconstitution.· 1week, 2 to 8 °C under sterile conditions after reconstitution. ·Please avoid repeated freeze-thaw cycles.
Buffer System:
10 mM PBS, pH 7.4.
Quality Statement:
Interleukin 7（IL-7）is a mature protein of 177 amino acids with a signal sequence of 25 aminoacids and a calculated mass of 17.4kDa. Recombinant human IL-7 stimulated theproliferation of murine pre-B cells and was active on cells harvested fromhuman bone marrow that are enriched for B-lineage progenitor cells.IL-7 is a proteinaceous biological response modifier that has a bioactivetertiary structure dependent on disulfide bond formation.IL-7-stimulated pro-B cells partially differentiated into a pre-B cellpopulation, on the basis of the loss of CD34 and terminal deoxynucleotidyl(TdT) expression, and the acquisition of cytoplasmic mu heavy chains.
Reference:
1. Proc Natl Acad Sci U S A. 1989 Jan;86(1):302-6.doi: 10.1073/pnas.86.1.302.2. J Biol Chem. 1997 Dec 26;272(52):32995-3000. doi:10.1074/jbc.272.52.32995.3. J Immunol. 1995 Jan 1;154(1):58-67.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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