Name:
GLP1R full length protein Flag Protein
Species Name:
Human
Label Name:
Flag Tag, His Tag
Marker Name:
Unconjugated
Accession:
P43220
Gene Id:
R24-F257, E262-K437, S193C, I196F, S225A, M233C, S271A, I317C, G318I, G361C, K346A, C347F, E387D
Molecular Weight:
57.3KDa
Purity:
Physical Appearance Name:
Liquid
Endotoxin Name:
<1EU/μg
Reconstitution:
Stability Storage:
-80°C
Buffer System:
20 mM HEPES pH 7.5, 150 mM NaCl, 0.05% (w/v) GDN, 0.005% (w/v) CHS.
Quality Statement:
A 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Popular product recommendations:
TGM2/Transglutaminase 2 Protein
UBE2D1 Protein
Popular categories:
T Cell CD Proteins
FGFR-3/CD333
