Name:
TEAD3 Protein
Synonyms:
DTEF1; ETFR 1; ETFR 1; TEAD5; TEF 5
Species Name:
Human
Label Name:
His Tag
Marker Name:
Unconjugated
Accession:
Q99594
Gene Id:
Arg218-Asp435HHHHHHHHRTIASSRLRLLEYSAFMEVQRDPDTYSKHLFVHIGQTNPAFSDPPLEAVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKFWADLNSTIQEGPGAFYGVSSQYSSADSMTISVSTKVCSFGKQVVEKVETEYARLENGRFVYRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTSRDSQETLLVIAFVFEVSTSEHGAQHHVYKLVKD
Molecular Weight:
27kDa (Reducing)
Purity:
＞95% by SDS-PAGE
Physical Appearance Name:
Liquid
Endotoxin Name:
<0.1EU/μg
Reconstitution:
Stability Storage:
·12 months from date of receipt, -20 °Cas supplied. ·1 month, 2 to 8 °C under sterileconditions after reconstitution. ·Please avoid repeated freeze-thaw cycles.
Buffer System:
20mTris, 300mNaCl, 20% glycerol, 5mM DTT, pH8.0
Quality Statement:
The transcriptional enhancer factor (TEF)multigene family is primarily functional in muscle-specific genes throughbinding to MCAT elements that activate or repress transcription of many genesin response to physiological and pathological stimuli. Among the TEF family,TEF-1, RTEF-1, and DTEF-1 are critical regulators of cardiac and smoothmuscle-specific genes during cardiovascular development and cardiac disordersincluding cardiac hypertrophy. Emerging evidence suggests that in addition tofunctioning as muscle-specific transcription factors, members of the TEF familymay be key mediators of gene expression induced by hypoxia in endothelial cellsby virtue of its multidomain organization, potential for post-translationalmodifications, and interactions with numerous transcription factors, which representa cell-selective control mediator of nuclear signaling.
Reference:
1.Yi Jin 1, Angela F Messmer-Blust（2011）Trends Cardiovasc Med.21:1
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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