Name:
TECK/CCL25 Protein
Synonyms:
Thymus Expressed Chemokine, CCL25
Species Name:
Human
Label Name:
No Tag
Marker Name:
Unconjugated
Accession:
O15444-1
Gene Id:
Gln24-Leu150MQGVFEDCCLAYHYPIGWAVLRRAWTYRIQEVSGSCNLPAAIFYLPKRHRKVCGNPKSREVQRAMKLLDARNKVFAKLHHNTQTFQAGPHAVKKLSSGNSKLSSSKFSNPISSSKRNVSLLISANSGL
Molecular Weight:
16kDa
Purity:
>95% by SDS-PAGE
Physical Appearance Name:
Lyophilized Powder
Endotoxin Name:
<0.1EU/μg
Reconstitution:
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability Storage:
12 months from date of receipt, -20 to -70 °C as supplied; 6 months, -20 to -70 °C under sterile conditions after reconstitution; 1 week, 2 to 8 °C under sterile conditions after reconstitution; Please avoid repeated freeze-thaw cycles.
Buffer System:
PBS, pH7.4
Quality Statement:
A novel CC chemokine was identified in the thymus of mouse and human and was designated TECK (thymus-expressed chemokine). TECK has weak homology to other CC chemokines and maps to mouse chromosome 8. Besides the thymus, mRNA encoding TECK was detected at substantial levels in the small intestine and at low levels in the liver. TECK has been reported to chemoattract dendritic cells, thymocytes, and activated macrophages. TECK is a specific agonist for a human orphan receptor called GPR-9-6. Human TECK also induced the in vitro migration of HEK 293/human GPR-9-6 cells. These results confirm that GPR-9-6 is a specific receptor for TECK. Recombinant human TECK is a protein containing 127 amino acid residues, including the four conserved cysteine residues present in CC chemokines.
Reference:
1.\tImmunity. 1997 Aug;7(2):291-301. doi: 10.1016/s1074-7613(00)80531-2. 2.\tJ Immunol. 1999 May 15;162(10):5671-5.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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