Name:
SCF Protein
Synonyms:
KITLG, FPH2, KL-1, Kitl, MGF, SCF, SF, SHEP7, KL
Species Name:
Human
Label Name:
No Tag
Marker Name:
Unconjugated
Accession:
P21583
Gene Id:
Glu26-Ala189MEGICRNRVTNNVKDVTKLVANLPKDYMITLKYVPGMDVLPSHCWISEMVVQLSDSLTDLLDKFSNISEGLSNYSIIDKLVNIVDDLVECVKENSSKDLKKSFKSPEPRLFTPEEFFRIFNRSIDAFKDFVVASETSDCVVSSTLSPEKDSRVSVTKPFMLPPVA
Molecular Weight:
19kDa
Purity:
>95% by SDS-PAGE
Physical Appearance Name:
Lyophilized Powder
Endotoxin Name:
<0.1EU/μg
Reconstitution:
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability Storage:
12 months from date of receipt, -20 to -70 °C as supplied; 6 months, -20 to -70 °C under sterile conditions after reconstitution; 1 week, 2 to 8 °C under sterile conditions after reconstitution; Please avoid repeated freeze-thaw cycles.
Buffer System:
20mM Tris, 200mM NaCl, pH8.0
Quality Statement:
Stem Cell Factor is also known as SCF, kit-ligand, KL, steel factor, KITLG, FPH2, KL-1, Kitl, MGF, SCF, SF, or SHEP7, and is a cytokine that binds to the c-Kit receptor (CD117). Stem cell factors perform their biological functions by binding to and activating the receptor tyrosine kinase c-Kit. The human SCF gene encodes for a 273 amino acid transmembrane protein, which contains a 25 amino acid N-terminal signal sequence, a 189 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 36 amino acid cytoplasmic domain. Stem cell factor (SCF) has been shown to stimulate the proliferation of myeloid, erythroid, and lymphoid progenitor cells in bone marrow culture and has been shown to work synergically with colony-stimulating factors.
Reference:
1.\tReview Physiol Rev. 2012 Oct;92(4):1619-49. doi: 10.1152/physrev.00046.2011.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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