CHIR-99021 HCl
CHIR-99021 (CT99021) is an inhibitor of GSK-3α/β with IC50 of 10 nM/6.7 nM, respectively. CHIR-99021 induces the activation of glycogen synthase (GS) in insulin receptor-expressing CHO-IR cells.
Product Name:
CHIR-99021 HCl
>Also Known As:
6-(2-(4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-ylamino)ethylamino)nicotinonitrile hydrochloride
>Catalog No.:
F6190
>Size:
5 mg
>CAS:
252917-06-9
>Formula:
C22H18Cl2N8.HCl
>Molecular Weight:
501.8 Da
>Form:
Lyophilized powder
>Quality Assurance:
>98% by HPLC and NMR
>Source:
Synthetic
>Storage:
Eligible for room temperature shipping. Store at -80°C upon receiving
>PDF Data Sheet:
Download PDF datasheet
>Image(s):
N/A
>Shipping Method:
Room temperature shipping
>References:
Ring DB, et al. (2003) Diabetes 52(3), 588-595. Maytansinol 18480744
