Name:
DMBT1 Protein
Synonyms:
GP340 Protein, muclin
Species Name:
Human
Label Name:
His Tag
Marker Name:
Unconjugated
Accession:
Accession#:Q9UGM3-2
Gene Id:
Thr20-Ser220, with C-terminal 8*HisTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISGGGSHHHHHHHH
Molecular Weight:
35-50kDa
Purity:
>95% by SDS-PAGE
Physical Appearance Name:
Lyophilized Powder
Endotoxin Name:
<0.1EU/μg
Reconstitution:
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability Storage:
12 months from date of receipt, -20 to -70 °C as supplied; 6 months, -20 to -70 °C under sterile conditions after reconstitution; 1 week, 2 to 8 °C under sterile conditions after reconstitution; Please avoid repeated freeze-thaw cycles.
Buffer System:
PBS, pH7.4
Quality Statement:
DMBT1(missing in malignant brain tumor 1), also known as glycoprotein 340 and salivary agglutinin, is a secreted protein that belongs to the DMBT1 family. DMBT1 is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is visible on the membrane, while in other macrophages, it is strongly expressed in the phagosome/phagolysosomal chamber. It is expressed in the lungs, trachea, salivary glands, small intestine and stomach. In the pancreas, it is expressed in certain cells on the island of Langerhans. DMBT1 plays an important role in innate immune response.Recent studies identify DMBT1 as a high affinity ligand of Siglec-8 in human airways.
Reference:
1．\tReview Int J Mol Sci . 2010;11(12):5212-33. doi: 10.3390/ijms1112521. Epub 2010 Dec 17.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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