Name:
IdeZ Protease Protein
Synonyms:
IgG endopeptidase
Species Name:
Streptococcus pyogenes
Label Name:
His Tag
Marker Name:
Unconjugated
Accession:
Q0PIW1
Gene Id:
N.A
Molecular Weight:
36kDa
Purity:
>95% by SDS-PAGE
Physical Appearance Name:
Liquid
Endotoxin Name:
null
Reconstitution:
N.A
Stability Storage:
12 months from date of receipt, -20 to -70 °C as supplied; 6 months, -20 to -70 °C under sterile conditions after reconstitution; 1 week, 2 to 8 °C under sterile conditions after reconstitution; Please avoid repeated freeze-thaw cycles.
Buffer System:
20 mM Tris-HCl, 50 mM NaCl, 1 mM EDTA, pH 7.5
Quality Statement:
IdeZ Protease secreted by the Streptococcus equi subspecies zooepidemicus. This product is an engineered recombinant protease over expressed in Escherichia coli. It can specifically identify IgG, and perform enzyme digestion at specific sites in the hinge region of the antibody, and produce F(ab’)2 fragments and Fc fragments, which can identify human and other animal IgG, such as mouse, rabbit, monkey, sheep and human animal chimeric IgG, etc, It can be used for structural characterization analysis of antibodies and fusion protein drugs.
Reference:
1.Shi S, Mcleod B, Magnelli P, et al. The Utility of IdeZ Protease in Glycan Profiling of Therapeutic Antibodies[J]. Glycobiology, 2016(12):26. 2.Cheng-Wei H, Jie P, Yu-Qing O, et al. Characteristics of IgG degradation enzyme IdeZ in Streptococcus equi ssp. zooepidimicus[J]. Chinese Journal of Preventive Veterinary Medicine, 2018.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Popular product recommendations:
GBA/Glucosylceramidase Protein
ARL2BP Protein
Popular categories:
IL-36 gamma
FGF-6
