SerpinC1/Antithrombin III Protein

Name:
SerpinC1/Antithrombin III Protein

Synonyms:
AT3, ATIII

Species Name:
Mouse

Label Name:
His Tag

Marker Name:
Unconjugated

Accession:
P32261

Gene Id:
His33-Asn465, with C-terminal 8*HisHGNPVDDICIAKPRDIPVNPLCIYRSPGKKATEEDGSEQKVPEATNRRVWELSKANSRFATNFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLKQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSDLVSANRLFGDKSLTFNESYQDVSEVVYGAKLQPLDFKENPEQSRVTINNWVANKTEGRIKDVIPQGAINELTALVLVNTIYFKGLWKSKFSPENTRKEPFYKVDGQSCPVPMMYQEGKFKYRRVAEGTQVLELPFKGDDITMVLILPKPEKSLAKVEQELTPELLQEWLDELSETMLVVHMPRFRTEDGFSLKEQLQDMGLIDLFSPEKSQLPGIVAGGRDDLYVSDAFHKAFLEVNEEGSEAAASTSVVITGRSLNPNRVTFKANRPFLVLIREVALNTIIFMGRVANPCVNGGGSHHHHHHHH

Molecular Weight:
55-72kDa (Reducing)

Purity:
＞95% by SDS-PAGE

Physical Appearance Name:
Lyophilized Powder

Endotoxin Name:
<0.1EU/μg

Reconstitution:
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability Storage:
·12 months from date of receipt, -20 to -70 °C as supplied. ·1 month, 2 to 8 °C under sterile conditions after reconstitution. ·Please avoid repeated freeze-thaw cycles.

Buffer System:
PBS, pH7.4

Quality Statement:
The gene SerpinC1encodes a serine protease inhibitor named Antithrombin III (ATIII).Thisprotease demonstrates both anticoagulant and anti-inflammatory action. ATIII isthe most important coagulation factor inhibitor, and even minor changes inATIII can significantly alter the risk of thromboembolism. ATIII can alsosuppress inflammation via a coagulation-dependent or -independent effect.Moreover, apart from ATIII deficiency, ATIII and its gene SerpinC1 may also berelated to many diseases (e.g. hypertension, kidney diseases). The presentreview summarizes how ATIII affects the progress of kidney disease and itsmechanism.

Reference:
1.Zeyuan Lu. Feng Wang. SerpinC1/Antithrombin IIIin kidney-related diseases. Clinical Science (2017) 131 823–831.

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Popular product recommendations:
PD-L1 Protein
G-CSF Protein
Popular categories:
Serpin A10
Cyclin-Dependent Kinase 6 (CDK6)

Author: Adenosylmethionine- apoptosisinducer

Related Posts