Name:
MOG Protein
Synonyms:
BTN6, BTNL11, MOGIG2, NRCLP7, Myelin oligodendrocyte glycoprotein
Species Name:
Mouse
Label Name:
His Tag
Marker Name:
Unconjugated
Accession:
Q61885
Gene Id:
Gly29-Gly153,with C-terminal 8*HisGQFRVIGPGYPIRALVGDEAELPCRISPGKNATGMEVGWYRSPFSRVVHLYRNGKDQDAEQAPEYRGRTELLKETISEGKVTLRIQNVRFSDEGGYTCFFRDHSYQEEAAMELKVEDPFYWVNPGGGGSHHHHHHHH
Molecular Weight:
19-22kDa (Reducing)
Purity:
＞95% by SDS-PAGE
Physical Appearance Name:
Lyophilized Powder
Endotoxin Name:
<0.1EU/μg
Reconstitution:
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability Storage:
·12 months from date of receipt, -20 to -70 °C as supplied. ·1 month, 2 to 8 °C under sterile conditions after reconstitution. ·Please avoid repeated freeze-thaw cycles.
Buffer System:
PBS, pH7.4
Quality Statement:
Myelinoligodendrocyte glycoprotein (MOG) is a transmembrane protein belonging toimmunoglobulin superfamily. Mouse MOG issynthesized with a 28 amino acid (aa) signal sequence, a 128 aa extracellulardomain (ECD) containing an Ig-like domain, a 21 aa transmembrane domain, and a69 aa cytosolic fragment featuring a hydrophobic domain that associates withthe cytoplasmic face of the plasma membrane. MOG is expressed exclusively byoligodendrocytes in the central nervous system (CNS) and is localized to the outerlayer of the myelin sheath as well as in the oligodendrocyte plasma membrane.This makes MOG a potential target of cellular and humoral immune responses ininflammatory demyelinating diseases.
Reference:
1. Reindl, M. et al. (2013) Nat. Rev.Neurol. 9:455.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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