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Name:
CDH17/LI-cadherin Protein

Synonyms:
Cadherin-17, HPT-1

Species Name:
Cynomolgus

Label Name:
His Tag

Marker Name:
Unconjugated

Accession:
XP_005563762.2

Gene Id:
Gln23-Met787, with C-terminal 10*His QEGKFSGPLKPMTFSIYEGQEPSQIIFQFKANPPAVTFELTGETDNIFKIEREGLLYYTKALDRETRSTHNLQVAALDANGAIVEGPVPITIEVKDVNDNRPTFLQSKYEGSVRQNSRPGKPFLYVNATDLDDPATPNGQLSYQIVIQLPMINNVMYFQINNKTGGISLTREGSQELNPAKNPSYNLVISVKDMGGQSENSFSDTTSVDIIVTENIWKAPEPVEMVENSTDPHPIKITQVRWNDPGAQYSLVDKEKLPRFPFSIDQEGDIYVTQPLDREEKDAYVFYAVAKDEYGKPLSYPLEIHVKVQDINDNPPTCPSPVTVFEVQENERLGNSIGTLTAHDSDEENTANSLLNYRIVEQTPKLPMDGLFLIQTYAGMLQLAKQSLKKQDTPQYNLTIEVSDKDFKTLCFVQINVIDINDQIPIFEKSDYGNLTLAEDTNVGSTILTIQATDADEPFTGSSKILYHVIKGDSEGRLGVDTDPHTNTGYVIIKKPLDFETAAISNIVFKAENPEPLVSGVTYNASSFAKFTLFVTDVNEAPEFSQYVFQAKVSEDVAIGTKVGNVTAKDPEGLDISYSLRGDTRGWLKIDHVTGEIFSVAPLDREAGSPYRVQVVATEVGGSSLSSVSQFHLILTDVNDNPPRLAKDYMDLYFCHPLSAPGSLIFEATDDDQHLFRGPHFTFSIASESLQNDWQVSKINGTHARLSTRHTDFEEKEYVVSIRINDGGRPPLESTVSLTVTFCSCGEDGCFRPAGHQPGIPTVGMGGGSGGGSHHHHHHHHHH

Molecular Weight:
95-110kDa

Purity:
>95% by SDS-PAGE

Physical Appearance Name:
Lyophilized Powder

Endotoxin Name:
<0.1EU/μg

Reconstitution:
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability Storage:
12 months from date of receipt, -20 to -70 °C as supplied; 6 months, -20 to -70 °C under sterile conditions after reconstitution; 1 week, 2 to 8 °C under sterile conditions after reconstitution; Please avoid repeated freeze-thaw cycles.

Buffer System:
PBS, pH7.4

Quality Statement:
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily,genes encoding calcium-dependent,membrane-associated glycoproteins.Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular region,7 cadherin domains,and a transmembrane region but lacking the conserved cytoplasmic domain.Cadherins preferentially interact with themselves in a homophilic manner in connecting cells;Cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine.It’s also involved in intestinal peptide transport.

Reference:
1.\tChen R ,Cao J ,Chen J , et al.Single nucleotide polymorphisms in the CDH17 gene of colorectal carcinoma[J].World Journal of Gastroenterology,2012,18(48):7251-7261. 2.\tLong Z ,Zhou M ,Fu J , et al.Association between cadherin-17 expression and pathological characteristics of gastric cancer:A meta-analysis[J].World Journal of Gastroenterology,2015,21(12):3694-3705.

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Author: Adenosylmethionine- apoptosisinducer