Name:
FGF-10 Protein
Synonyms:
FGF-10, Fibroblast Growth Factor-10, FGFA, Keratinocyte growth factor-2, KGF2
Species Name:
Mouse
Label Name:
No Tag
Marker Name:
Unconjugated
Accession:
O35565
Gene Id:
Ser62-Thr209MSSAGRHVRSYNHLQGDVRWRRLFSFTKYFLTIEKNGKVSGTKNEDCPYSVLEITSVEIGVVAVKAINSNYYLAMNKKGKLYGSKEFNNDCKLKERIEENGYNTYASFNWQHNGRQMYVALNGKGAPRRGQKTRRKNTSAHFLPMTIQT
Molecular Weight:
17kDa
Purity:
>95% by SDS-PAGE & RP-HPLC
Physical Appearance Name:
Lyophilized Powder
Endotoxin Name:
<1EU/μg
Reconstitution:
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability Storage:
12 months from date of receipt, -20 to -70 °C as supplied; 6 months, -20 to -70 °C under sterile conditions after reconstitution; 1 week, 2 to 8 °C under sterile conditions after reconstitution; Please avoid repeated freeze-thaw cycles.
Buffer System:
20mM Tris, 50mM NaCl, 2mM DTT, pH8.0
Quality Statement:
Fibroblast growth factor 10 (FGF-10), a secreted heparin-binding protein, is a member of the fibroblast growth factor (FGF) family and is also known as Keratinocyte Growth Factor-2 (KGF-2). FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-10 exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies revealed that genetic variants of FGF10 were associated with extreme myopia in adults.
Reference:
1、Hubert F. et al. (2022) FGF10 promotes cardiac repair through a dual cellular mechanism increasing cardiomyocyte renewal and inhibiting fibrosis. Cardiovasc Res. 118(12): 2625-2637.2、Sun W. et al. (2019) Cytokine fibroblast growth factor 10 (FGF10) polymorphisms are associated with risk of myopia in young children. J Cell Biochem. 120(9): 15241-15247.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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