Product Name :
Rabbit anti-PAOX Polyclonal Antibody(Center)
Synonym :
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase; Polyamine oxidase; PAOX; PAO
Host :
Rabbit
Species Reactivity:
Human, Mouse
Specificity :
This PAOX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 467-496 amino acids from the Central region of human PAOX.
Predicted Reactivity:
Applications :
WB~~1:1000IHC-P~~1:50~100
Immunogen:
Concentration :
Purification :
Clonality:
Polyclonal Antibody
Storage Temp.:
Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long term storage store at -20 ° C in small aliquots to prevent free that cycles
Research areas :
Signal Transduction
Background :
Flavoenzyme which catalyzes the oxidation of N(1)- acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)- acetylspermidine >N(1),N(12)-diacylspermine >>spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.
UniProt :
Q6QHF9
Additional information:
Product Details FAQ Citations(0) Video Pictures Documents |Overview |Description Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) |Synonym Peroxisomal N(1)-acetyl-spermine/spermidine oxidase; Polyamine oxidase; PAOX; PAO |Host Rabbit |Specificity This PAOX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 467-496 amino acids from the Central region of human PAOX. |Species Reactivity Human, Mouse |Applications WB~~1:1000IHC-P~~1:50~100 |Properties |Clonality Polyclonal Antibody |Isotype Rabbit Ig |Storage Temp. Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long term storage store at -20 ° C in small aliquots to prevent free that cycles |Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |Research areas Signal Transduction |Target |Background Flavoenzyme which catalyzes the oxidation of N(1)- acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)- acetylspermidine >N(1),N(12)-diacylspermine >>spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. |Cellular localization Peroxisome. Cytoplasm |UniProt Q6QHF9 |Tips:This product is for research use only. Not for use in diagnostic prodcedures.
Rabbit anti-PAOX Polyclonal Antibody(Center)
Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.Related websites: https://www.medchemexpress.com/antibodies.html
2628280-40-8 manufacturer 205640-90-0 site PMID:27809438 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com
