Name:
TGF-α Protein
Synonyms:
Species Name:
Human
Label Name:
No Tag
Marker Name:
Unconjugated
Accession:
P01135
Gene Id:
Val40-Ala89VVSHFNDCPDSHTQFCFHGTCRFLVQEDKPACVCHSGYVGARCEHADLLA
Molecular Weight:
30-33kDa (Reducing)
Purity:
>95% by SDS-PAGE
Physical Appearance Name:
Lyophilized Powder
Endotoxin Name:
<1EU/μg
Reconstitution:
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability Storage:
12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution.1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles.
Buffer System:
20mM Tris, 150mM NaCl, pH8.0
Quality Statement:
Transforming growth factor alpha (TGF-α), a polypeptide of 5.5kDa that is partially homologous to epidermal growth factor (EGF), is important in the control of glial and Schwann cell proliferation and survival of differentiated neurons. TGF-α is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF-β to promote anchorage-independent cell proliferation in soft agar. Although TGF-α commonly acts via autocrine or paracrine signaling in solid tissues, it can also mediate paracrine signaling by activated macrophages, monocytes, neutrophils, and eosinophils.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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