Product Name :
MIM1
Description:
MIM1 is an inhibitor of Mcl-1, an antiapoptotic Bcl-2 family protein that selectively engages the canonical groove of Mcl-1, inhibiting its ability to bind BH3 domains. MIM1 induces caspase-3/7 activation and cell death in Mcl-1-dependent leukemia cells.
CAS:
509102-00-5
Molecular Weight:
347.43
Formula:
C17H21N3O3S
Chemical Name:
4-[(1E)-[2-(cyclohexylimino)-4-methyl-2,3-dihydro-1,3-thiazol-3-yl]iminomethyl]benzene-1,2,3-triol
Smiles :
CC1=CSC(=NC2CCCCC2)N1/N=C/C1=CC=C(O)C(O)=C1O
InChiKey:
RGGFUBMUOVFZEF-LDRVEFRDSA-N
InChi :
InChI=1S/C17H21N3O3S/c1-11-10-24-17(19-13-5-3-2-4-6-13)20(11)18-9-12-7-8-14(21)16(23)15(12)22/h7-10,13,21-23H,2-6H2,1H3/b18-9+,19-17-
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Crystal Violet Biological Activity
Shelf Life:
≥12 months if stored properly.Curcumin Purity & Documentation
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:33179817
Additional information:
MIM1 is an inhibitor of Mcl-1, an antiapoptotic Bcl-2 family protein that selectively engages the canonical groove of Mcl-1, inhibiting its ability to bind BH3 domains. MIM1 induces caspase-3/7 activation and cell death in Mcl-1-dependent leukemia cells.|Product information|CAS Number: 509102-00-5|Molecular Weight: 347.43|Formula: C17H21N3O3S|Synonym:|MIM 1|MIM-1|Inhibitor of Mcl-1|Chemical Name: 4-[(1E)-[2-(cyclohexylimino)-4-methyl-2,3-dihydro-1,3-thiazol-3-yl]iminomethyl]benzene-1,2,3-triol|Smiles: CC1=CSC(=NC2CCCCC2)N1/N=C/C1=CC=C(O)C(O)=C1O|InChiKey: RGGFUBMUOVFZEF-LDRVEFRDSA-N|InChi: InChI=1S/C17H21N3O3S/c1-11-10-24-17(19-13-5-3-2-4-6-13)20(11)18-9-12-7-8-14(21)16(23)15(12)22/h7-10,13,21-23H,2-6H2,1H3/b18-9+,19-17-|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
