Product Name :
sAJM589
Description:
sAJM589 is a Myc inhibitor which potently disrupts the Myc-Max heterodimer with an IC50 of 1.8 μM.
CAS:
2089-82-9
Molecular Weight:
246.26
Formula:
C16H10N2O
Chemical Name:
5, 10-diazatetraphen-12-ol
Smiles :
OC1=CC2=NC3=CC=CC=C3N=C2C2=CC=CC=C21
InChiKey:
WZBDRAAGHRCRKM-UHFFFAOYSA-N
InChi :
InChI=1S/C16H10N2O/c19-15-9-14-16(11-6-2-1-5-10(11)15)18-13-8-4-3-7-12(13)17-14/h1-9,19H
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
sAJM589 is a Myc inhibitor which potently disrupts the Myc-Max heterodimer with an IC50 of 1.8 μM.|Product information|CAS Number: 2089-82-9|Molecular Weight: 246.26|Formula: C16H10N2O|Chemical Name: 5, 10-diazatetraphen-12-ol|Smiles: OC1=CC2=NC3=CC=CC=C3N=C2C2=CC=CC=C21|InChiKey: WZBDRAAGHRCRKM-UHFFFAOYSA-N|InChi: InChI=1S/C16H10N2O/c19-15-9-14-16(11-6-2-1-5-10(11)15)18-13-8-4-3-7-12(13)17-14/h1-9,19H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 5 mg/mL (20.30 mM; Need ultrasonic)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.Amifampridine site |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|sAJM589 potently disrupts the Myc-Max heterodimer to reduce Myc protein levels in a dose dependent manner, with an IC50 of 1.Enmetazobactam site 8 μM.PMID:32946344 sAJM589 suppresses cellular proliferation in diverse Myc-dependent cancer cell lines and anchorage independent growth of Raji cells.|References:|Choi SH, et al. Targeted Disruption of Myc-Max Oncoprotein Complex by a Small Molecule. ACS Chem Biol. 2017 Nov 17;12(11):2715-2719.Products are for research use only. Not for human use.|
