Name:
STX4 Protein
Synonyms:
STX4A, Syntaxin-4
Species Name:
Human
Label Name:
His Tag
Marker Name:
Unconjugated
Accession:
Q12846
Gene Id:
Met1-Leu275, with N-terminal 8*His HHHHHHHHMRDRTHELRQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADENYNSVNTRMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSGQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMINRIEKNILSSADYVERGQEHVKTALENQKKARKKKVL
Molecular Weight:
33kDa
Purity:
＞95% by SDS-PAGE
Physical Appearance Name:
Lyophilized Powder
Endotoxin Name:
<0.1EU/μg
Reconstitution:
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability Storage:
12 months from date of receipt, -20 to -70 °C as supplied; 6 months, -20 to -70 °C under sterile conditions after reconstitution; 1 week, 2 to 8 °C under sterile conditions after reconstitution; Please avoid repeated freeze-thaw cycles.
Buffer System:
PBS, pH7.4
Quality Statement:
Syntaxin-4, a member of the Qa sensitive factor attachment protein receptor (SNARE) syntaxin family has been implicated in fusion events at the plasma membrane in a number of cells in the immune system. This protein enables sphingomyelin phosphodiesterase activator activity, and is active in glutamatergic synapse and postsynapse. Study demonstrates that syntaxin-4 plays a critical role in the secretion of IgE from plasma cells and sheds some light on the mechanisms by which these cells constitutively traffic vesicles to the surface for secretion. Together with STXB3 and VAMP2, it may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes and in docking of synaptic vesicles at presynaptic active zones (By similarity).
Reference:
1.\tBiochem Biophys Res Commun. 2013 Oct 11;440(1):163-7. doi: 10.1016/j.bbrc.2013.09.058.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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