Name:
Biotinylated GLP-1R Protein
Synonyms:
GLP-1 receptor; GLP1R; GLP-1R; GLP-1-R; glucagon-like peptide 1 receptor; MGC138331
Species Name:
Human
Label Name:
Avi Tag, His Tag
Marker Name:
Biotin
Accession:
P43220-1
Gene Id:
Ala21-Glu139 AGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEGGGSHHHHHHHHGLNDIFEAQKIEWHE
Molecular Weight:
25-33kDa (Reducing)
Purity:
＞95% by SDS-PAGE
Physical Appearance Name:
Lyophilized Powder
Endotoxin Name:
<1EU/μg
Reconstitution:
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability Storage:
·12 months from date of receipt, -20 to -70 °C as supplied. ·1 month, 2 to 8 °C under sterile conditions after reconstitution. ·Please avoid repeated freeze-thaw cycles.
Buffer System:
PBS, pH7.4.
Quality Statement:
Glucagon-like peptide-1 receptor (GLP-1R) is a class B G-protein-coupled receptor. Human GLP-1R consists of an N-terminal, extracellular domain (ECD) containing 6 conserved cysteine residues and a transmembrane domain with seven membrane-spanning alpha-helices, characteristic of GPCRs. Activation of GLP-1R signaling regulates secretion of insulin from pancreatic beta -cells in a glucose-dependent manner. Glucagon-like peptide 1 receptor (GLP1R) signaling has been shown to have antipsychotic properties in animal models and to impact glucose-dependent insulin release, satiety, memory, and learning in man.
Reference:
1. Article Open Access Published: 09 March 2020Nature Communications volume 11, Article number: 1272 (2020) Cite this article.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Popular product recommendations:
FGF-21 Proteinmanufacturer
HMGB1/HMG-1 Proteinsupplier
Popular categories:
BTN3A1/CD277
Ring Finger Protein 43
