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Name:
SCF Protein

Synonyms:
KITLG, FPH2, KL-1, Kitl, MGF, SCF, SF, SHEP7, KL

Species Name:
Mouse

Label Name:
No Tag

Marker Name:
Unconjugated

Accession:
P20826

Gene Id:
Lys26-Ala189MKEICGNPVTDNVKDITKLVANLPNDYMITLNYVAGMDVLPSHCWLRDMVIQLSLSLTTLLDKFSNISEGLSNYSIIDKLGKIVDDLVLCMEENAPKNIKESPKRPETRSFTPEEFFSIFNRSIDAFKDFMVASDTSDCVLSSTLGPEKDSRVSVTKPFMLPPVA

Molecular Weight:
18kDa (Reducing)

Purity:
>95% by SDS-PAGE

Physical Appearance Name:
Lyophilized Powder

Endotoxin Name:
<0.1EU/μg

Reconstitution:
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability Storage:
·12 months from date of receipt, -20 to-70 °C as supplied. ·1 month, 2 to 8 °C under sterileconditions after reconstitution. ·Please avoid repeated freeze-thaw cycles.

Buffer System:
20mM Tris, 100mM NaCl, pH8.0

Quality Statement:
Stem Cell Factor is also known as SCF,kit-ligand, KL, steel factor, KITLG, FPH2, KL-1, Kitl, MGF, SCF, SF, or SHEP7,and is a cytokine that binds to the c-Kit receptor (CD117). Stem cell factorsperform their biological functions by binding to and activating the receptortyrosine kinase c-Kit. The human SCF gene encodes for a 273 amino acidtransmembrane protein, which contains a 25 amino acid N-terminal signalsequence, a 189 amino acid extracellular domain, a 23 amino acid transmembranedomain, and a 36 amino acid cytoplasmic domain. Stem cell factor (SCF) has beenshown to stimulate the proliferation of myeloid, erythroid, and lymphoidprogenitor cells in bone marrow culture and has been shown to work synergicallywith colony-stimulating factors.

Reference:
1.Review Physiol Rev. 2012 Oct;92(4):1619-49. doi:10.1152/physrev.00046.2011​

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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Author: Adenosylmethionine- apoptosisinducer