Name:
Biotinylated BCMA/TNFRSF17 Protein
Synonyms:
TNFRSF17, CD269, BCM
Species Name:
Cynomolgus
Label Name:
Avi Tag, His Tag
Marker Name:
Unconjugated
Accession:
XP_005591343.1
Gene Id:
Met1-Ala53MLQMARQCSQNEYFDSLLHDCKPCQLRCSSTPPLTCQRYCNASMTNSVKGMNAGGGSGGGSHHHHHHHHHHGLNDIFEAQKIEWHE
Molecular Weight:
15-20kDa (Reducing)
Purity:
>95% by SDS-PAGE
Physical Appearance Name:
Lyophilized Powder
Endotoxin Name:
<0.1EU/μg
Reconstitution:
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability Storage:
·12 months from date of receipt, -20 to -70 °C as supplied. ·1 month, 2 to 8 °C under sterile conditions after reconstitution. ·Please avoid repeated freeze-thaw cycles.
Buffer System:
PBS, pH7.4.
Quality Statement:
B Cell Maturation Antigen (BCMA) also referred to as TNFRSF17 or CD269, is a transmembrane glycoprotein member of the tumor necrosis factor receptor (TNFR) superfamily. BCMA is a type III membrane protein containing one extracellular cysteine rich domain. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.
Reference:
1. Gene ID: 608, updated on 18-Aug-2023.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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