Name:
LIF Protein
Synonyms:
Species Name:
Human
Label Name:
No Tag
Marker Name:
Unconjugated
Accession:
P15018
Gene Id:
Ser23-Phe202SPLPITPVNATCAIRHPCHNNLMNQIRSQLAQLNGSANALFILYYTAQGEPFPNNLDKLCGPNVTDFPPFHANGTEKAKLVELYRIVVYLGTSLGNITRDQKILNPSALSLHSKLNATADILRGLLSNVLCRLCSKYHVGHVDVTYGPDTSGKDVFQKKKLGCQLLGKYKQIIAVLAQAF
Molecular Weight:
19-20kDa (Non-reducing)
Purity:
>95%by SDS-PAGE&RP-HPLC
Physical Appearance Name:
Lyophilized Powder
Endotoxin Name:
<0.1EU/μg
Reconstitution:
Reconstitute at 0.5-1mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability Storage:
· 12 months from date of receipt, -20 to -70 °C as supplied. · 6 months, -20 to -70 °C under sterile conditions after reconstitution.· 1 week, 2 to 8 °C under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Buffer System:
20mM Tris, 200mM NaCl, pH8.0
Quality Statement:
Leukaemia inhibitory factor (LIF) is produced by many different cell types and has pleiotropic actions. LIF stimulates the differentiation of the macrophage cell line M1, and the proliferation of haematopoietic stem cells. In vivo, it has profound effects on haematopoiesis, particularly in combination with other cytokines such as IL-3, causing increased platelet formation. LIF allows embryonic stem cells to remain in an undifferentiated state and can maintain their proliferation in culture. LIF stimulates synthesis of acute phase proteins by liver cells, increases bone resorption, stimulates differentiation of cholinergic nerves and loss of body fat.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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