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Name:
IdeZ Protease Protein

Synonyms:
IdeZ

Species Name:
Streptococcus equi subsp. Zooepidemicus

Label Name:
No Tag

Marker Name:
Unconjugated

Accession:
Q0PIW1

Gene Id:

Molecular Weight:
36kDa (Reducing)

Purity:
>95% by SDS-PAGE

Physical Appearance Name:
Liquid

Endotoxin Name:
null

Reconstitution:

Stability Storage:
·12 months from date of receipt, -20 to-70 °C as supplied. ·1 month, 2 to 8 °C under sterile conditions

Buffer System:
Tris-HC, pH7.5.

Quality Statement:
IdeZ Protease secreted by the Streptococcus equisubspecies zooepidemicus. This product is an engineered recombinant proteaseover expressed in Escherichia coli. It can specifically identify IgG, andperform enzyme digestion at specific sites in the hinge region of the antibody,and produce F(ab’)2 fragments and Fc fragments, which can identify human and otheranimal IgG, such as mouse, rabbit, monkey, sheep and human animal chimeric IgG,etc, It can be used for structural characterization analysis of antibodies andfusion protein drugs.

Reference:
[1] Shi S, Mcleod B, Magnelli P, et al. The Utility of IdeZProtease (Tag Free) in Glycan Profiling of Therapeutic Antibodies[J].Glycobiology, 2016(12):26.[2]Cheng-Wei H, JieP, Yu-Qing O ,et al. Characteristics of IgG degradation enzymeIdeZ in Streptococcus equi ssp. zooepidimicus[J].Chinese Journal of PreventiveVeterinary Medicine, 2018..

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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Author: Adenosylmethionine- apoptosisinducer