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Name:
PLGF-2/PLGF/PGF Protein

Synonyms:
PGF, PLGF, PLGF2, PLGF, PGFL, SHGC-10760

Species Name:
Mouse

Label Name:
His Tag

Marker Name:
Unconjugated

Accession:
P49764-1

Gene Id:
Val19-Pro158, with C-terminal 8*HisVHSQGALSAGNNSTEVEVVPFNEVWGRSYCRPMEKLVYILDEYPDEVSHIFSPSCVLLSRCSGCCGDEGLHCVPIKTANITMQILKIPPNRDPHFYVEMTFSQDVLCECRPILETTKAERRKTKGKRKRSRNSQTEEPHPGGGSHHHHHHHH

Molecular Weight:
25-33kDa

Purity:
>95% by SDS-PAGE

Physical Appearance Name:
Lyophilized Powder

Endotoxin Name:
<0.1EU/μg

Reconstitution:
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability Storage:
12 months from date of receipt, -20 to -70 °C as supplied; 6 months, -20 to -70 °C under sterile conditions after reconstitution; 1 week, 2 to 8 °C under sterile conditions after reconstitution; Please avoid repeated freeze-thaw cycles.

Buffer System:
PBS, pH7.4

Quality Statement:
Placental growth factor (PGF), also known as vascular endothelial growth factor-related proteins PLGF and PLGF2, is a member of the vascular endothelial growth factor (VEGF) family. PLGF is a three-dimensional structure composed of 149 amino acids. PLGF is a dimeric glycoprotein formed by a 69kD α chain and a 34kD β chain connected by disulfide bond, with a unique cystine junction. These junctions are characterized by eight spatially conserved cysteines that are involved in intramolecular and intermolecular disulfide bond formation. PLGF is a pleiotropic factor affects different cell types and regulates various biological responses.PGF is not only activated during angiogenesis and endothelial cell growth, stimulating their proliferation and migration, but also promoting cell tumor growth.

Reference:
1.\tReview ProgRetin Eye Res.2019 Mar;69:116-136.doi: 10.1016/j.preteyeres. 2018.10.006. Epub 2018 Oct 30.

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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Author: Adenosylmethionine- apoptosisinducer