Name:
TNF-α Protein
Synonyms:
TNF-alpha, Tumor Necrosis Factor, Cachectin, Tumor Necrosis Factor Ligand Superfamily Member 2, TNF-a, TNF, TNFA, TNFSF2
Species Name:
Rhesus macaque
Label Name:
No Tag
Marker Name:
Unconjugated
Accession:
P48094
Gene Id:
Val77-Leu233 VRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELTDNQLVVPSEGLYLIYSQVLFKGQGCPSNHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINLPDYLDFAESGQVYFGIIAL
Molecular Weight:
17.3kDa
Purity:
>95% by SDS-PAGE
Physical Appearance Name:
Lyophilized Powder
Endotoxin Name:
<0.1EU/μg
Reconstitution:
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability Storage:
12 months from date of receipt, -20 to -70 °C as supplied; 6 months, -20 to -70 °C under sterile conditions after reconstitution; 1 week, 2 to 8 °C under sterile conditions after reconstitution; Please avoid repeated freeze-thaw cycles.
Buffer System:
PBS, 2mM TCEP, pH 7.4
Quality Statement:
Tumour Necrosis Factor α (TNFα), is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and is responsible for a diverse range of signalling events within cells, leading to necrosis or apoptosis. The protein is also important for resistance to infection and cancers. In view of these facts, TNF-α has been recommended as an important target for discovering drugs for autoimmune and inflammatory diseases and cancer.
Reference:
1.\tMicrosc Res Tech. 2000 Aug 1;50(3):184-95.2.\tMethods Mol Biol. 2021;2248:271-279. doi: 10.1007/978-1-0716-1130-2_21.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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