Name:
SerpinF1/PEDF Protein
Synonyms:
SERPINF1,Serpin F1,PEDF,PIG35,EPC-1
Species Name:
Human
Label Name:
His Tag
Marker Name:
Unconjugated
Accession:
P36955
Gene Id:
Gln20-Pro418,with C-terminal 8*HisQNPASPPEEGSPDPDSTGALVEEEDPFFKVPVNKLAAAVSNFGYDLYRVRSSTSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPDIHGTYKELLDTVTAPQKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLTGNPRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDSPDFSKITGKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDPRGPGGGSHHHHHHHH
Molecular Weight:
47-53kDa (Reducing)
Purity:
＞95% by SDS-PAGE
Physical Appearance Name:
Lyophilized Powder
Endotoxin Name:
<0.1EU/μg
Reconstitution:
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability Storage:
·12 months from date of receipt, -20 to -70 °C as supplied. ·1 month, 2 to 8 °C under sterile conditions after reconstitution. ·Please avoid repeated freeze-thaw cycles.
Buffer System:
PBS, pH7.4
Quality Statement:
Human SERPINF1 genecodes for pigment epithelium-derived factor, a secreted glycoprotein and memberof the SERPIN superfamily. Pigment epithelium-derived factor, also known asPEDF, Serpin F1, and SERPINF1, is a multiple functional protein that has bothanti-angiogenic activity and neurotrophic activity at the same time.PEDF hasaffinity for PEDF-receptor (PEDF-R), a membrane-linked lipase encoded by thePNPLA2 gene.PEDF is also responsible for apoptosis of endothelial cells eitherthrough the p38 MAPK pathway or through the FAS/FASL pathway.PEDF has a varietyof functions including antiangiogenic, antitumorigenic, and neurotrophicproperties.
Reference:
1.Published online 2022 Feb 15. doi: 10.1016/j.pep.2022.106072.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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