Name:
BMPRIA/ALK-3 Protein
Synonyms:
10q23del Protein, Human; ACVRLK3 Protein, Human; ALK3 Protein, Human
Species Name:
Human
Label Name:
His Tag
Marker Name:
Unconjugated
Accession:
P36894
Gene Id:
Gln24-Arg152,with C-terminal 8*HisQNLDSMLHGTGMKSDSDQKKSENGVTLAPEDTLPFLKCYCSGHCPDDAINNTCITNGHCFAIIEEDDQGETTLASGCMKYEGSDFQCKDSPKAQLRRTIECCRTNLCNQYLQPTLPPVVIGPFFDGSIRGGGSHHHHHHHH
Molecular Weight:
20-28kDa (Reducing)
Purity:
＞95% by SDS-PAGE
Physical Appearance Name:
Lyophilized Powder
Endotoxin Name:
<0.1EU/μg
Reconstitution:
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability Storage:
·12 months from date of receipt, -20 to -70 °C as supplied. ·1 month, 2 to 8 °C under sterile conditions after reconstitution. ·Please avoid repeated freeze-thaw cycles.
Buffer System:
PBS, pH7.4
Quality Statement:
Activin receptor-LikeKinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA(BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) whichbelong to the transforming growth factor beta (TGF-β) superfamily.The bone morphogenetic protein (BMP)receptors are a family of transmembrane serine/threonine kinases that includethe type I receptors BMPR1A (this protein) and BMPR1B and the type II receptorBMPR2. ALK-3 plays an essential role in the formation of embryonic ventralabdominal wall, and abrogation of BMP signaling activity due to gene mutationsin its signaling components could be one of the underlying causes ofomphalocele at birth.
Reference:
1.Proc Natl Acad Sci U S A. 2002 Mar5;99(5):2878-83. doi:10.1073/pnas.042390499. Epub 2002 Feb 19.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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