Name:
IGF-I Protein
Synonyms:
IGF-I Protein, IGF1A Protein, IGFI Protein
Species Name:
Human
Label Name:
No Tag
Marker Name:
Unconjugated
Accession:
P05019
Gene Id:
Gly49-Ala118MGPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA
Molecular Weight:
8-9kDa (Non-Reducing)
Purity:
＞95% by SDS-PAGE
Physical Appearance Name:
Lyophilized Powder
Endotoxin Name:
<0.1EU/μg
Reconstitution:
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability Storage:
·12 months from date of receipt, -20 to -70 °C as supplied. ·1 month, 2 to 8 °C under sterile conditions after reconstitution. ·Please avoid repeated freeze-thaw cycles.
Buffer System:
50mM NaAc, pH6.0.
Quality Statement:
Insulin-like growth factor 1 (IGF-1) is also known as somatomedin C,IGF1A, IGFI, sulfation factor, and is a hormone similar in molecular structureto Insulin. IGF-1 Protein binds to cell surface receptor IGF type 1 receptor,which abbreviated as \”IGF1R\” and modulates growth in many tissues,such as nervous tissue, lymphoid tissue, reproductive tissue, smooth muscle,endothelium, and bone. IGF-1 Protein also mediates neuroprotective mechanism.It is produced primarily by the liver as an endocrine hormone as well as intarget tissues in a paracrine/autocrine fashion. IGF-1 consists of 70 aminoacids in a single chain with three intramolecular disulfide bridges. IGF-1 hasa molecular weight of 7649 daltons.
Reference:
1.Jansen M., et al.(1983)Sequence of cDNA encoding human Insulin-like growth factor I precursor. Nature306:609-611.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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