Name:
EGFL6 Protein
Synonyms:
Egfl6, Maeg, MGC141463 Protein
Species Name:
Mouse
Label Name:
His Tag
Marker Name:
Unconjugated
Accession:
Q9JJZ5
Gene Id:
Thr287-Gly550, with C-terminal 8*HisTMKKKVKLKMVTPRPASTRVPKVNLPYSSEEGVSRGRNYDGEQKKKEEGKRERLEEEKGEKTLRNEVEQERTLRGDVFSPKVNEAEDLDLVYVQRKELNSKLKHKDLNISVDCSFDLGVCDWKQDREDDFDWHPADRDNDVGYYMAVPALAGHKKNIGRLKLLLPNLTPQSNFCLLFDYRLAGDKVGKLRVFVKNSNNALAWEETKNEDGRWRTGKIQLYQGIDTTKSVIFEAERGKGKTGEIAVDGVLLVSGLCPDDFLSVEGGGGSHHHHHHHH
Molecular Weight:
38-42kDa (Reducing)
Purity:
＞95% by SDS-PAGE
Physical Appearance Name:
Lyophilized Powder
Endotoxin Name:
<0.1EU/μg
Reconstitution:
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability Storage:
· 12months from date of receipt, -20 to -70 °C as supplied.· 1week, 2 to 8 °C under sterile conditions after reconstitution.·Please avoid repeated freeze-thaw cycles.
Buffer System:
PBS, pH7.4
Quality Statement:
EGFL6, a member ofthe EGF-like superfamily, plays an important role during embryonic developmentand has been implicated in promotion of tumor angiogenesis without affectingwound healing. Importantly, expression of EGFL6 in cancer cells and tumorendothelial cells not only increased tumor angiogenesis but also promotedmigration of cancer cells. Members ofthis superfamily are characterized by the presence of EGF-like repeats and areoften involved in the regulation of cell cycle, proliferation, and developmentalprocesses. EGFL6 gene is expressed early during development, and its expressionhas been detected in lung and meningioma tumors.
Reference:
1. An, J., Du, Y., Fan, X. et al. EGFL6promotes breast cancer by simultaneously enhancing cancer cell metastasis and stimulatingtumor angiogenesis. Oncogene 38, 2123–2134 (2019).https://doi.org/10.1038/s41388-018-0565-9.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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