Name:
CDH17/LI-cadherin Protein
Synonyms:
Cadherin-17, HPT-1
Species Name:
Cynomolgus
Label Name:
His Tag
Marker Name:
Unconjugated
Accession:
XP_005563762.2
Gene Id:
Gln23-Met787, with C-terminal 10*His QEGKFSGPLKPMTFSIYEGQEPSQIIFQFKANPPAVTFELTGETDNIFKIEREGLLYYTKALDRETRSTHNLQVAALDANGAIVEGPVPITIEVKDVNDNRPTFLQSKYEGSVRQNSRPGKPFLYVNATDLDDPATPNGQLSYQIVIQLPMINNVMYFQINNKTGGISLTREGSQELNPAKNPSYNLVISVKDMGGQSENSFSDTTSVDIIVTENIWKAPEPVEMVENSTDPHPIKITQVRWNDPGAQYSLVDKEKLPRFPFSIDQEGDIYVTQPLDREEKDAYVFYAVAKDEYGKPLSYPLEIHVKVQDINDNPPTCPSPVTVFEVQENERLGNSIGTLTAHDSDEENTANSLLNYRIVEQTPKLPMDGLFLIQTYAGMLQLAKQSLKKQDTPQYNLTIEVSDKDFKTLCFVQINVIDINDQIPIFEKSDYGNLTLAEDTNVGSTILTIQATDADEPFTGSSKILYHVIKGDSEGRLGVDTDPHTNTGYVIIKKPLDFETAAISNIVFKAENPEPLVSGVTYNASSFAKFTLFVTDVNEAPEFSQYVFQAKVSEDVAIGTKVGNVTAKDPEGLDISYSLRGDTRGWLKIDHVTGEIFSVAPLDREAGSPYRVQVVATEVGGSSLSSVSQFHLILTDVNDNPPRLAKDYMDLYFCHPLSAPGSLIFEATDDDQHLFRGPHFTFSIASESLQNDWQVSKINGTHARLSTRHTDFEEKEYVVSIRINDGGRPPLESTVSLTVTFCSCGEDGCFRPAGHQPGIPTVGMGGGSGGGSHHHHHHHHHH
Molecular Weight:
95-110kDa
Purity:
＞95% by SDS-PAGE
Physical Appearance Name:
Lyophilized Powder
Endotoxin Name:
<0.1EU/μg
Reconstitution:
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability Storage:
12 months from date of receipt, -20 to -70 °C as supplied; 6 months, -20 to -70 °C under sterile conditions after reconstitution; 1 week, 2 to 8 °C under sterile conditions after reconstitution; Please avoid repeated freeze-thaw cycles.
Buffer System:
PBS, pH7.4
Quality Statement:
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily,genes encoding calcium-dependent,membrane-associated glycoproteins.Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular region,7 cadherin domains,and a transmembrane region but lacking the conserved cytoplasmic domain.Cadherins preferentially interact with themselves in a homophilic manner in connecting cells;Cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine.It’s also involved in intestinal peptide transport.
Reference:
1.\tChen R ,Cao J ,Chen J , et al.Single nucleotide polymorphisms in the CDH17 gene of colorectal carcinoma[J].World Journal of Gastroenterology,2012,18(48):7251-7261. 2.\tLong Z ,Zhou M ,Fu J , et al.Association between cadherin-17 expression and pathological characteristics of gastric cancer:A meta-analysis[J].World Journal of Gastroenterology,2015,21(12):3694-3705.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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