Name:
FGF-8c Protein
Species Name:
Mouse
Label Name:
No Tag
Marker Name:
Unconjugated
Accession:
P37237
Gene Id:
Gln23-Arg268 MQVRSAAQKRGPGAGNPADTLGQGHEDRPFGQRSRAGKNFTNPAPNYPEEGSKEQRDSVLPKVTQRHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR
Molecular Weight:
28-29kDa
Purity:
>95% by SDS-PAGE
Physical Appearance Name:
Lyophilized Powder
Endotoxin Name:
<1EU/μg
Reconstitution:
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability Storage:
12 months from date of receipt, -20 to -70 °C as supplied; 6 months, -20 to -70 °C under sterile conditions after reconstitution; 1 week, 2 to 8 °C under sterile conditions after reconstitution; Please avoid repeated freeze-thaw cycles.
Buffer System:
20mM Tris, 100mM NaCl, pH8.0
Quality Statement:
Fibroblast Growth Factor 8 was originally identified as an androgen-dependent growth of mouse mammary carcinoma cells. The primary transcript of mouse FGF-8 is alternatively spliced to generate at least 8 secreted isoforms that differ at their amino terminus. The differences between the isoforms exist in the number of potential N-linked glycosylation sites. In mouse, the eight isoforms are labeled as 8a through 8h. Human FGF-8 is limited to only four isoforms. Only isoforms 8a, 8b, 8e, and 8f are synthesized in humans. Mouse and human 8a and 8b isoforms are 100% identical, while the 8e and 8f isoforms are 98% identical. The FGF-8 isoforms differentially activate the various alternatively spliced forms of the FGF receptors 1-3, and FGF receptor 4. The isoform FGF-8c activates FGF R3c and FGF R4.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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