PD-L2/B7-DC Protein | Adenosylmethionine

Name:
PD-L2/B7-DC Protein

Synonyms:
PD-L2, B7-DC, CD273, PDCD1 ligand 2, PDCD1L2, PDCD1LG2

Species Name:
Cynomolgus

Label Name:
null

Marker Name:
Unconjugated

Accession:
XP_005581839

Gene Id:
Leu20-Pro219, with C-terminal Human IgG1 FcLFTVTVPKELYIIEHGSNATLECNFDTGSHVNLGAITASLQKVENDTSPHRERATLLEEQLSLGKALFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKIDTHILKVPETDEVELTCQATGYPLAEVSWPNISVPANTSHSRTPEGLYQVTSVLRLKPHPGRNFSCVFWNAQVRELTLASIDLQSQIEPRTHPIEGRMDPKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK

Molecular Weight:
60-75kDa

Purity:
>95% by SDS-PAGE

Physical Appearance Name:
Lyophilized Powder

Endotoxin Name:
<0.1EU/μg

Reconstitution:
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability Storage:
12 months from date of receipt, -20 to -70 °C as supplied; 6 months, -20 to -70 °C under sterile conditions after reconstitution; 1 week, 2 to 8 °C under sterile conditions after reconstitution; Please avoid repeated freeze-thaw cycles.

Buffer System:
PBS, pH7.4

Quality Statement:
B7-DC [also known as programmed death ligand 2 (PD-L2)] is a costimulatory molecule expressed predominantly on dendritic cells (DCs) and macrophages. In addition to its coinhibitory receptor, programmed death receptor 1 (PD-1), evidence suggests that B7-DC interacts with an unidentified costimulatory receptor on T cells. B7-DC mutants with selective binding capacity for the costimulatory receptor may be effective in stimulating antitumor immune responses, while avoiding the inhibitory effects of PD-1.

Reference:
1、Kojima M. et al. (2014) Fusion Protein of Mutant B7-DC and Fc Enhances the Antitumor Immune Effect of GM-CSF-secreting Whole-cell Vaccine. J Immunother. 37(3): 147-154.

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Popular product recommendations:
IL-22 Protein
VEGF-DD Protein
Popular categories:
Death Receptor 6
G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D)

Author: Adenosylmethionine- apoptosisinducer

Related Posts