Name:
Fc γ RIV/CD16-2 Protein
Synonyms:
Low affinity immunoglobulin gamma Fc region receptor IV；CD16-2；Fc γ RIV
Species Name:
Mouse
Label Name:
His Tag
Marker Name:
Unconjugated
Accession:
A0A0B4J1G0-1
Gene Id:
GLQKAVVNLDPKWVRVLEEDSVTLRCQGTFSPEDNSIKWFHNESLIPHQDANYVIQSARVKDSGMYRCQTALSTISDPVQLEVHMGWLLLQTTKWLFQEGDPIHLRCHSWQNRPVRKVTYLQNGKGKKYFHENSELLIPKATHNDSGSYFCRGLIGHNNKSSASFRISLGDPGSPSMFPPWHQGGGSGGGSHHHHHHHH
Molecular Weight:
28-35kDa(Reducing)
Purity:
＞95%, by SDS-PAGE under reducing conditions
Physical Appearance Name:
Lyophilized Powder
Endotoxin Name:
<0.1EU/μg
Reconstitution:
Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation .
Stability Storage:
· 12 months from date of receipt, -20 to -70 °C as supplied. · 6 months, -20 to -70 °C under sterile conditions after reconstitution.· 1 week, 2 to 8 °C under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Buffer System:
PBS, pH7.4
Quality Statement:
Fc γ RIV (Low affinity immunoglobulin gamma Fc region receptor IV), also known as CD16-2 (Fc γ RIV), belongs to the Fc γ receptor family. Fc γ receptors can be divided into three types: Fc γ RI (CD64), Fc γ RII (CD32) and Fc γ RIII (CD16). Fc γ RI (CD64) has a high affinity for IgG monomers, while Fc γ RII (CD32) and Fc γ RIII (CD16) have relatively low affinity for IgG. Human CD16 is encoded by two genes, Fc γ RIIIA and Fc γ RIIIB. The gene sequence of CD16-2 is more similar to human Fc γ RIIIA protein. Fc γ RIV binding with IgG2a can promote osteocyte differentiation, while binding with IgE can promote macrophage-mediated phagocytosis, antigen presentation and pro-inflammatory cytokines production.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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