Ces to the host. Despite the fact that AMCase, Ym1, Fizz1, and Fizz2 are all expressed at the internet site of infection, Ym1 and Fizz1 are also induced from the APCs of the draining LN. This implies a broader IL-15 Receptor Proteins Biological Activity perform for these two proteins and suggests that they perform at numerous levels during a Th2-mediated immune response.ACKNOWLEDGMENTS We thank Anjie Harris, Karen Gilmour, and especially Yvonne Harcus for outstanding technical support. We thank Simon Fillatreau, Alison Crawford, Steve Anderton, and David Gray for reagents and useful comments and Adam Balic for crucial reading through on the manuscript. This function was supported by the Wellcome Believe in and also the Healthcare Investigation Council Uk.REFERENCES one. Allen, J. E., R. A. Lawrence, and R. M. Maizels. 1996. APC from mice harbouring the filarial nematode, Brugia malayi, prevent cellular proliferation but not cytokine production. Int. Immunol. 8:14351. 2. Anderton, S. M., N. J. Viner, P. Matharu, P. A. Lowrey, and D. C. Wraith. 2002. Influence of the dominant cryptic epitope on autoimmune T cell tolerance. Nat. Immunol. three:17581. three. Bain, O., and S. Babayan. 2003. Behaviour of filariae: morphological and anatomical signatures of their lifestyle design inside of the arthropod and vertebrate hosts. Filaria J. 2:16. 4. Blagoev, B., I. Kratchmarova, M. M. Nielsen, M. M. Fernandez, J. Voldby, J. S. Andersen, K. Kristiansen, A. IL-10 Receptor Proteins Recombinant Proteins Pandey, and M. Mann. 2002. Inhibition of adipocyte differentiation by resistin-like molecule alpha. Biochemical characterization of its oligomeric nature. J. Biol. Chem. 277:420112016. five. Bonini, S., G. Rasi, M. L. Bracci-Laudiero, A. Procoli, and L. Aloe. 2003. Nerve growth issue: neurotrophin or cytokine Int. Arch. Allergy Immunol. 131:804. six. Boot, R. G., E. F. Blommaart, E. Swart, K. Ghauharali-van der Vlugt, N. Bijl, C. Moe, A. Location, and J. M. Aerts. 2001. Identification of the novel acidic mammalian chitinase distinct from chitotriosidase. J. Biol. Chem. 276:67706778. seven. Boot, R. G., G. H. Renkema, M. Verhoek, A. Strijland, J. Bliek, T. M. de Meulemeester, M. M. Mannens, and J. M. Aerts. 1998. The human chitotriosidase gene. Nature of inherited enzyme deficiency. J. Biol. Chem. 273: 256805685. 8. Braun, A., E. Appel, R. Baruch, U. Herz, V. Botchkarev, R. Paus, C. Brodie, and H. Renz. 1998. Purpose of nerve growth aspect in a mouse model of allergic airway irritation and asthma. Eur. J. Immunol. 28:3240251. 9. Chang, N. C., S. I. Hung, K. Y. Hwa, I. Kato, J. E. Chen, C. H. Liu, and a. C. Chang. 2001. A macrophage protein, Ym1, transiently expressed for the duration of irritation is a novel mammalian lectin. J. Biol. Chem. 276:174977506. 10. deSchoolmeester, M. L., M. C. Tiny, B. J. Rollins, and K. J. Else. 2003. Absence of CC chemokine ligand 2 final results in an altered Th1/Th2 cytokine balance and failure to expel Trichuris muris infection. J. Immunol. 170:46934700. eleven. Dransfield, I., E. Stephenson, and C. Haslett. 1996. Recognition of apoptotic cells by phagocytes, p. 14974. In T. G. Cotter and S. J. Martin (ed.), Procedures in apoptosis: a user’s manual. Portland Press Ltd., London, Uk. 12. Falcone, F. H., P. Loke, X. Zang, A. S. MacDonald, R. M. Maizels, and J. E. Allen. 2001. A Brugia malayi homolog of macrophage migration inhibitory factor reveals an essential link among macrophages and eosinophil recruitment during nematode infection. J. Immunol. 167:5348354. 13. Fallon, P. G., C. L. Emson, P. Smith, as well as a. N. McKenzie. 2001. IL-13 overexpression predisposes to anaphylaxis following a.