St (IFS) along with the selfreport questionnaires (BDI, STAI and CDS). In
St (IFS) plus the selfreport questionnaires (BDI, STAI and CDS). In a different session, JM and participants from this group underwent fMRI scanning. Within the second step of the study, the patient and the second manage group, EAC, were evaluated utilizing empathy tasks (IRI and EPT) in individual sessions.Graph Network.theorymetricsInteroceptiveemotionalResults Sociodemographic, clinical and neuropsychological resultsSociodemographic, clinical and neuropsychological outcomes of JM and the IAC sample are provided in Table . No important variations in age (t 2.52, p 0 Zcc two.67), years of formal education (t 20.76, p 0.24, Zcc 20.84) and gender (they have been all males) were identified in between JM along with the IAC group. No patientcontrol differences had been observed in either the neuropsychological EF evaluation (IFS) (t 2.56, p 0.09, Zcc 2.70), depression (t 0.9, p 0.2, Zcc 0.99) and anxiousness state and trait (STAIS, t .26, p 0.4, Zcc .38; STAIT, t 0.87, p 0.two, Zcc 0.96).Cambridge Depersonalization ScaleJM showed substantial variations in the IAC group in practically all the subscales of the CDS that measure the intensity in the Tyr-D-Ala-Gly-Phe-Leu subjective expertise of depersonalization symptoms (memories recall, t four.76, p,0.0, Zcc five.2; alienation, t 5.40, p,0.0, Zcc five.9; physique encounter, t 5.39, p,0.0, Zcc five.92), except for emotional numbing (t 0.79, p 0.24, Zcc 0.87). Additionally, JM presented drastically greater scores in comparison to controls in the subscales from the CDS that assess frequency (t 7.4, p, 0.0, Zcc 8.3) and duration (t 7 p,0.0, Zcc 7.78) of depersonalizationderealization episodes. Lastly, considerable differences were identified in between the patient and controls within the total score (t 7.36, p,0.0, Zcc 8.06) (see also Fig. ).Interoceptive resultsHeartbeat Detection Activity (HBD). No significant variations have been discovered in between the patient along with the IAC sample in theInteroception and Emotion in DDTable . Demographic, clinical and neuropsychological assessment.JM Sociodemographic data Age Formal education (in years) IFS Total Store Affective screening Depression (BDI) Anxiousness State (STAIS) Anxiousness Trait (STAIT) doi:0.37journal.pone.0098769.t00 8 28 39 2330 23TpZccIAC Simple2.52 20.0. 0.2.67 20.M 28.2; SD 3. (253) M 7.four; SD .67 (59)two.0.2.M 27; SD two.34 (250)0.9 .26 0.0.two 0.four 0.0.99 .38 0.M 2.8; SD five.2 (02) M 26.2; SD .30 (258) M 30.2; SD 9.20 (226)very first two motorauditory circumstances (initially motorauditory t 0.62, p 0.28, Zcc 0.68; second motorauditory t two.25, p 0.four, Zcc two.37). In these situations, participants were told to adhere to recorded heartbeats. Comparable benefits have been obtained when comparing the patient’s and controls’ performance within the first interoceptive situation (t 2.50, p 0.0, Zcc two.65). On the other hand, controls showed a significantly higher Accuracy Index than the patient in the second interoceptive situation (t 0.49, p,0.0, Zcc 25). In these circumstances, participants had been told to stick to their very own heartbeats without having any auditory cue. In the following condition, where subjects listen on the web to their own heartbeats by means of headphones, each groups presented equivalent final results (t 0, p 0.50, Zcc 0). Ultimately, considerable differences have been located within the final interoceptive situations; as within the second interoceptive situation, controls exhibited a higher Accuracy Index than the patient PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/21425987 (third interoceptive situation, t 23.five, p 0.02, Zcc 2 3.45; fourth interoceptive situation t 23.96, p,0.0, Zcc 4.33). In these, subjects had been requested t.