SB216763
SB216763 is a potent and selective glycogen synthase kinase-3 (GSK-3) inhibitor. It competes with ATP and potently inhibits the activity α and β isozymes of GSK-3. It acts as neuroprotectant and prevents neuronal cell death induced by PI3-kinase pathway.
Product Name:
SB216763
>Also Known As:
3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
>Catalog No.:
F6200
>Size:
5 mg
>CAS:
280744-09-4
>Formula:
C19H12N2O2Cl2
>Molecular Weight:
371.22 Da
>Form:
Lyophilized powder
>Quality Assurance:
>98% by HPLC and NMR
>Source:
Synthetic
>Storage:
Eligible for room temperature shipping. Store at -80°C upon receiving
>PDF Data Sheet:
Download PDF datasheet
>Image(s):
N/A
>Shipping Method:
Room temperature shipping
>References:
Cross DA, et al. (2001) J Neurochem 77:94-102. AMG-337 18480811
