Pifithrin-alpha
Pifithrin-alpha is an inhibitor of p53, reversibly inhibits p53-dependent transactivation of p53-responsive genes and apoptosis. Pifithrin-α (10 μM) enhances cell survival after genotoxic stress such as UV irradiation and treatment with DNA damage compounds including doxorubicin, etopoxide, and paclitaxel.
Product Name:
Pifithrin-alpha
>Also Known As:
Pifithrin-α, Ethanone, 1-(4-methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)-, hydrobromide (1:1)
>Catalog No.:
F7160
>Size:
5 mg
>CAS:
63208-82-2
>Formula:
C16H18N2OS.HBr
>Molecular Weight:
367.3 Da
>Form:
Lyophilized powder
>Quality Assurance:
>98% by HPLC and NMR
>Source:
Synthetic
>Storage:
Eligible for room temperature shipping. Store at -80°C upon receiving
>PDF Data Sheet:
Download PDF datasheet
>Image(s):
N/A
>Shipping Method:
Room temperature shipping
>References:
Komarov, PG, et al. (1999) Science 285, 1733-1737 BMS-754807 18481490/
