LY294002
LY294002 is a selective phosphatidylinositol 3-kinase (PI3K) inhibitor. LY294002 inhibit PI3Kα/δ/β with IC50 of 0.5 μM/0.57 μM/0.97 μM, respectively; more stable in solution than Wortmannin, and also blocks autophagosome formation.
Product Name:
LY294002
>Also Known As:
2-morpholin-4-yl-8-phenylchromen-4-one
>Catalog No.:
F6110
>Size:
5 mg
>Molecular Weight:
307.34 Da
>Species:
N/A
>Source:
Synthetic
>Stock:
Powder
>Concentration:
N/A
>Quality Assurance:
>99% by HPLC and NMR
>Storage:
Eligible for room temperature shipping. Store at -20°C upon receiving; protect from air and light
>PDF Data Sheet:
PDF Datasheet
>NCBI RefSeq:
N/A
>Image(s):
(Click image to enlarge)
Purity check of Necrostatin-1 by HPLC
>Shipping Method:
Room temperature shipping
>References:
1. Vlahos CJ, et al. (1994) Journal of Biological Chemistry 269 (7): 5241–5248.
2. Blommaart EF, et al. (1997) Eur. J. Biochem. 243: 240–246.
3. Maira SM, et al. (2009) Biochem Soc Trans. 37(Pt 1):265-72. Verteporfin 18480196