KU-60019
KU-60019 is a potent ATM kinase inhibitor (IC50 = 6.3 nM) in cell-free assays. Exhibits little to no nonspecific target effects against a panel of 229 protein kinases, including ATR and DNA-PKcs. It is a highly effective radiosensitizer.
Product Name:
KU-60019
>Also Known As:
2-((2S,6R)-2,6-dimethylmorpholino)-N-(5-(6-morpholino-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide
>Catalog No.:
F8120
>Size:
5 mg
>CAS:
925701-49-1
>Formula:
C30H33N3O5S
>Molecular Weight:
547.67 Da
>Form:
Lyophilized powder
>Quality Assurance:
>98% by HPLC and NMR
>Source:
Synthetic
>Storage:
Eligible for room temperature shipping. Store at -80°C upon receiving
>PDF Data Sheet:
Download PDF datasheet
>Image(s):
N/A
>Shipping Method:
Room temperature shipping
>References:
Golding SE, et al. (2009) Mol Cancer Ther, 8(10), 2894-2902. TRV130 (hydrochloride) 18481955