HA-Ub-VME
A potent, irreversible and specific inhibitor of deubiquitinating enzymes (DUBs) that is prepared by chemical synthesis. It is N-terminally tagged with an HA-tag (YPYDVPDYA), which allows for sensitive identification or purification of DUBs since it is specifically recognized by anti-HA antibodies. The HA tag is separated from the Ub N-terminus by two aminohexanoic acid (Ahx) linkers for efficient recognition of the HA tag.
Product Name:
HA-Ub-VME
>Also Known As:
N/A
>Catalog No.:
M1010
>Size:
25 µg
>Molecular Weight:
9913 Da by MS
>Species:
Human
>Source:
Synthetic
>Stock:
Product in lyophilized powder form.
>Concentration:
N/A
>Quality Assurance:
≥95% by RP-HPLC
>Storage:
Powder at −20°C; solution at −80°C. Avoid multiple freeze/thaw cycles.
>PDF Data Sheet:
PDF Datasheet， MSDS
>NCBI RefSeq:
N/A
>Image(s):
(Click image to enlarge)
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Coomassie-stained SDS-PAGE Lane 1: HA-Ub-VME Lane 2: Ubiquitin Lane 3: Molecular weight markers
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>Shipping Method:
Room temperature shipping
>References:
1. de Jong et al., (2012) ChemBioChem 13, 2251.
2. Borodovsky et al., (2001) EMBO J. 20, 5187.
3. Borodovsky et al., (2002) Chemistry and Biology 9, 1149.
4. El Oualid et al., (2010) Angew. Chem. Int. Ed. 49, 10149. NLG919 18469960
