GST-hHR23B (Rad23B)
hHR23A and hHR23B are the human homologues of yeast Rad23. Rad23 can interact with the Rpn10 and Rpn1 subunits of the 26S proteasome via its N-terminal Ub-like domain (UBL). Rad23 also contains two Ub-associated domains (UBA), through which it binds polyubiquitinated proteins for proteasomal degradation. In addition, Rad23 can also bind DNA repair factors to regulate nucleotide excision repair from UV damage.
Product Name:
GST-hHR23B (Rad23B)
>Also Known As:
P58; HR23B; HHR23B
>Catalog No.:
I1110
>Size:
25 µg
>Molecular Weight:
43.2 kDa
>Species:
Human
>Source:
Bacterial recombinant
>Stock:
20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
>Concentration:
See tube label
>Quality Assurance:
~90% by SDS-PAGE, see datasheet for gel image
>Storage:
Store at -80°C; avoid multiple freeze-thaw cycles
>PDF Data Sheet:
PDF Datasheet， MSDS
>NCBI RefSeq:
NM_002874
>Image(s):
No
>Shipping Method:
Dry ice shipping
>References:
1. Watkins JF, et al. (1993) Mol Cell Biol 13(12), 7757 – 7765.
2. Chen L, et al. (2002) Mol Cell Biol 22(13), 4902 – 4913.
3. Wade SL, et al. (2010) Transcription 1, 22–26. N-Acetyl-Calicheamicin 18482903
