GST-USP4
Usp4 is a member of the ubiquitin-specific protease family of deubiquitinating enzyme. A number of substrates of Usp4 have been identified, including TRIM21, TRAF2, TRAF6, RIG-1, RIP1, PDK1, TAK1 and etc. Usp4-mediated deubiquitination was found to regulate several signaling pathways, including the AKT signaling, RIG-1-mediated antiviral response, TNFα-induced signaling, and the Wnt signaling.
Product Name:
GST-USP4
>Also Known As:
UNP; Unph
>Catalog No.:
H5410
>Size:
50 µg
>Molecular Weight:
108.6 kDa
>Species:
Human
>Source:
Bacterial recombinant
>Stock:
20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
>Concentration:
See tube label
>Quality Assurance:
~ 75% by SDS-PAGE, see datasheet for gel image
>Storage:
Store at -80°C; avoid multiple freeze-thaw cycles
>PDF Data Sheet:
PDF Datasheet， MSDS
>NCBI RefSeq:
NM_003363.3
>Image(s):
Images:
(Click image to enlarge)
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Coomassie-stained SDS-PAGE Lane 1: Molecular weight markers Lane 2: 5 µg purified GST-USP4 |
>Shipping Method:
Dry ice shipping
>References:
1. Wang L, et al. (2013) J Virol. 87(8):4507-15.
2. Zhang L, et al. (2012) Nat Cell Biol. 14(7):717-26.
3. Xiao N, et al. (2012) Biochem J. 441(3):979-86. Emricasan 18469177
