GST-USP30(57-517)
USP30(57-517) contains the catalytic domain of USP30 with the N-terminal membrane bound domain being deleted. USP30 deubiquitinates substrates of Parkin including MIRO1, TOMM20, MFN1, and MFN2 on mitochondrial membranes and functions to suppress mitophagy. It prefers cleavage of K6- and K11-linked polyubiquitin chains.
Product Name:
GST-USP30(57-517)
>Also Known As:
N/A
>Catalog No.:
H7810
>Size:
50 µg
>Molecular Weight:
51.5 kDa
>Species:
Human
>Source:
Bacterial recombinant
>Stock:
20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
>Concentration:
See tube label
>Quality Assurance:
~ 70% by SDS-PAGE
>Storage:
Store at -80°C; avoid multiple freeze-thaw cycles
>PDF Data Sheet:
PDF Datasheet， MSDS
>NCBI RefSeq:
NM_032663.4
>Image(s):
Images:
(Click image to enlarge)
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Coomassie-stained SDS-PAGE Lane 1: Molecular weight markers Lane 2: 5 µg purified OTUD6B |
>Shipping Method:
Dry ice shipping
>References:
1. Bingol B, et al. (2014) Nature 510: 370
2. Cunningham CN, et al. (2015) Nat Cell Biol. 17: 160
3. Wang, Y, et al. (2015) Autophagy 11: 595 EPZ-6438 18469238
