GST-USP15
Usp15 belongs to a family of deubiquitinating enzymes called the DU subfamily. Within this subfamily are Usp4 and Usp11 because they all contain an N-terminal “domain present in ubiquitin specific proteases” (DUSP) and ubiquitin-like (UBL) domains. Usp15 has been shown to play a role in stabilizing and activating caspase-3 during Paclitaxel-induced apoptosis. Usp15 also deubiquitinates IκBα which is an inhibitor of NF-κB.
Product Name:
GST-USP15
>Also Known As:
UNPH4; UNPH-2
>Catalog No.:
H6500
>Size:
50 µg
>Molecular Weight:
112.4 kDa
>Species:
Human
>Source:
Bacterial recombinant
>Stock:
20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
>Concentration:
See tube label
>Quality Assurance:
>70% by SDS-PAGE, see datasheet for gel image
>Storage:
Store at -80°C; avoid multiple freeze-thaw cycles
>PDF Data Sheet:
PDF Datasheet， MSDS
>NCBI RefSeq:
NM_001252078
>Image(s):
Images
(Click image to enlarge)
Coomassie-stained SDS-PAGE
Lane 1: Molecular weight markers
Lane 2: 5 µg purified GST-USP15
>Shipping Method:
Dry ice shipping
>References:
1. Reyes-Turcu FE,et al. (2009) Annu Rev Biochem 78, 363 – 397.
2. Xu M, et al. (2009) Biochem Biophys Res Commun 388, 366-371.
3. Harper S, et al. (2011) Biochemistry 50(37), 7995 – 8004. SBE-β-CD 1846921
