GST-UCHL3
Ubiquitin C-terminal hydrolase L3 (UchL3) is a deubiquitinase enzyme (DUB), which performs hydrolysis of the bond at the C terminus of the ubiquitin and trims down the polyubiquitin chain into monomers. UchL3 has been found to also process a ubiquitin-like substrate called NEDD8. It is 52% identical to the amino acid sequence of its related DUB, UchL1, and may share roles in maintaining neurons of the gracile tract in mice.
Product Name:
GST-UCHL3
>Also Known As:
GST-UCH-L3
>Catalog No.:
H1210
>Size:
25 µg
>Molecular Weight:
26.2 kDa
>Species:
Human
>Source:
Bacterial recombinant
>Stock:
20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
>Concentration:
See tube label
>Quality Assurance:
~95% by SDS-PAGE, see datasheet for gel image
>Storage:
Store at -80°C; avoid multiple freeze-thaw cycles
>PDF Data Sheet:
PDF Datasheet， MSDS
>NCBI RefSeq:
NM_001270952
>Image(s):
N/A
>Shipping Method:
Dry ice shipping
>References:
1. Pckard CM, Rose IA (1985) J Biol Chem 260(13), 7903 – 7910.
2. Day IN, et al. (1990) Biochem J 268(2), 521 – 524.
3. Wilkinson KD, et al. (1999) J Mol Biol 291(5), 1067 – 1077.
4. Kwon J (2007) Exp Anim 56(2), 71 – 77. Monomethyl auristatin E 18468767
