BX795
BX-795 is an inhibitor of 3-phosphoinositide-dependent kinase 1 (PDK1), as well as other kinases including TANK-binding kinase 1 (TBK1), Aurora B and IkB kinase ε (IKKε). BX-795 prevents TBK1- and IKKε-mediated activation of IRF3 and production of IFN-β.
Product Name:
BX795
>Also Known As:
N-(3-(5-iodo-4-(3-(thiophene-2-carboxamido)propylamino)pyrimidin-2-ylamino)phenyl)pyrrolidine-1-carboxamide
>Catalog No.:
F6150
>Size:
5 mg
>CAS:
702675-74-9
>Formula:
C23H26IN7O2S
>Molecular Weight:
591.47 Da
>Form:
Lyophilized powder
>Quality Assurance:
>98% by HPLC and NMR
>Source:
Synthetic
>Storage:
Eligible for room temperature shipping. Store at -80°C upon receiving
>PDF Data Sheet:
Download PDF datasheet
>Image(s):
N/A
>Shipping Method:
Room temperature shipping
>References:
Feldman RI, et al. (2005) J.Biol.Chem. 280 19867. OTS-964 18480294
